Tel: +44 (0) 1904 406082

Seralite®– FLC Urine* is a rapid lateral flow test for the qualitative in vitro diagnostic identification of abnormal kappa (K) and lambda (λ) immunoglobulin free light chains (FLCs) in human urine using immunochromatography. Used in conjunction with clinical findings the test is useful for screening for abnormal levels of FLCs at an early stage, guiding the choice of further diagnostic investigation of suspected cases.

Free light chains are an important diagnostic biomarker for identifying and monitoring B-cell dyscrasias, including multiple myeloma. In multiple myeloma excess production of FLCs frequently occurs which may exceed the capacity of the kidney to metabolise these antibody fragments leading to the presence of FLCs in the urine.

This rapid non-invasive test enables a free light chain service to be offered in all clinical laboratories without the need to send away samples. This enables the provision of FLC results in minutes rather than days or weeks, accelerating the choice of further diagnostic or clinical investigation.

Seralite® – FLC Urine utilises the CE marked and FDA registered ADxLR5® Reader System, where the kappa (K) and lambda (λ) results are presented individually on screen as “not elevated” or as “elevated”.

The assay utilises highly specific, anti-K and anti-λ monoclonal antibodies. These monoclonal antibodies have been comprehensively validated demonstrating that they detect FLCs secreted from both normal and neoplastic plasma cells and have a proven high degree of specificity and sensitivity.**

Further information about Seralite®– FLC Urine can be obtained by contacting a member of our team. Please contact us on either +44(0)1904 406080 or info@abingdonhealth.com.

*Seralite®– FLC Urine is not available for sale in the USA

**Please see Resources page for a full list of references.


FLC Urine LFD Controls

Dual Kappa and Lambda free light chain (FLC) Controls FLC LFD Controls […]

Read More

ADxLR5® Reader System

The ADxLR5® reader is used for quantitation of the Seralite® – FLC devices.

Read More

Sales and Distribution

Find out more about the sales and distribution network for Seralite® – FLC.

Read More

Featured Content
Connect

Follow Us

According to World Health Organization: - Half the world lacks access to essential health services - 100 million pe… https://t.co/Pt6XVu6hFU

20 April 2018

View more Tweets