Driving a safe return to normal life

This flexible, easy solution shows confirmation of those who have developed IgG neutralising antibodies following COVID-19 infection or vaccination.

Immunity status can be determined by the presence of neutralising antibodies. Therefore, the AbC-19™ solution is a powerful tool for providing businesses and communities with the confidence to return to normal life, safely.

  • Get tested
  • Prove COVID-19 IgG neutralising antibody status

FAQs.

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How can AbC-19™ unlock COVID-hit businesses?

  • Easily identify which employees or customers have COVID-19 neutralising antibodies
  • Provide operational peace of mind for business continuity and staff/customer well-being
  • Reassure clients they are in safe hands

With antibody testing there is no need to test twice a week. Meaning there are potential economic and logistics benefits.

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About AbC-19™ Rapid Test?

  • Confirm the presence of SARS-CoV-2 IgG neutralising antibodies in a small blood sample in 20 minutes
  • Sensitivity: 98.03%, Specificity: 99.56%*
  • CE marked for use by trained professionals**
  • Straightforward creation of antibody certificates
  • Minimal operator training required
  • Manufactured to ISO 13485 and underpinned by an established supply chain
  • Use in multiple testing locations such as pharmacies, medical centres or medical rooms in workplaces
  • 24/7 international customer support helpline

The AbC-19™ neutralising antibody test is manufactured at scale across multiple UK sites in state-of-the-art automated facilities. Each facility is connected to international logistics hubs.

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AbC-19™ Rapid Test and vaccines

Vaccines “train” the immune system to respond to harmful viruses. In the case of SARS-CoV-2 vaccine developers have focused on mimicking the virus’ Spike protein. Three vaccines all feature full-length SARS-CoV-2 spike trimers: Oxford University / AstraZeneca, Pfizer / BioNTeh, and Moderna.

Professor Lawrence S. Young, Virologist at University of Warwick Medical School:

”The AbC-19™ Rapid Test targets the IgG antibodies to the full spike protein of the SARS-CoV-2 virus and therefore has the potential to help identify the immune system’s response to the current three Medicines and Healthcare products Regulatory Agency (MHRA) approved vaccines.

The assay could help establish whether people’s immune systems are responding to the vaccine in the right way, and, ultimately, could be predictive of a protective immune response”.

For information on how AbC-19™ could inform vaccine deployment and usage, please download our whitepaper.

Download the AbC-19™ White Paper
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Frequently Asked Questions

  • A COVID-19 rapid neutralising antibody test, such AbC-19TM Rapid Test, is a lateral flow test that detects IgG antibodies to the SARS-CoV-2 spike protein.

    A positive result with a neutralising antibody rapid test holds significance in the context of the pandemic. Read our article ‘What are COVID-19 neutralising antibody rapid tests and why use them?’ to learn more.

  • The body produces antibodies that targets two specific parts of the SARS-CoV-2 virus: the Nucleocapsid protein and the Spike protein. The coronavirus nucleocapsid protein is a multi-functional protein whereas the spike protein is integral in penetrating human cells and initiating infection.

    Neutralising antibodies bind to the Spike protein thus interfering the virus’ ability to enter human cells. Immunologically, antibodies to the Nucleocapsid protein are necessary but in the context of pandemic the antibodies to Spike protein hold the key.

  • If taken at least 14 days following the onset of symptoms then the AbC-19™ Rapid Test has a sensitivity of 98.03% and a specificity of 99.56%. More details here.

    As detailed in the table below a known population of 450 negative samples were tested alongside 203 known positive samples. The positive population of 203 samples were obtained from donors at least 14 days after the onset of COVID-19 symptoms and were verified as positive using a commercial IgG SARS-CoV-2 ELISA kit.

    Positive Negative
    ELISA Positive 199 4
    Negative 2^ 448*

    * 98 pre-pandemic negative samples not tested by ELISA
    ^ 2 pre-pandemic negative samples not tested by ELISA

    Clinical Sensitivity and Specificity is as follows:
    Positive Predictive Agreement (Sensitivity): 98.03% (95% Cla : 95.03% – 99.46%)
    Negative Predictive Agreement (Specificity): 99.56% (95% Cla : 98.40% – 99.95%)

    Cross reactivity:
    Known positive serum samples from other viral infections were tested as follows (value in square brackets refers to the number tested) Seasonal Coronavirus (HCoV-NL63 [x5] and HCoV-229E [x5]), Influenza A [x5], H5N1 Influenza [x1], influenza B [x6] Respiratory Syncytial Virus (RSV) [x6], Haemophilus influenzae type b [x5] and Bordetella pertussis [x1]. No cross reactivity was observed, with all tests demonstrating a negative result using the AbC-19™ Rapid Test.
    Interference: A range of substances were tested using the AbC-19™ Rapid Test for positive and negative interference. No false positives or false negatives were recorded at the concentrations in the table below;

    Substance Upper limit of normal serum levels mg/dL Level Tested mg/dL
    Unconjugated Bilirubin 2 40
    Cholesterol (total) <200 400
    Triglyceride 200 1,500
    IgG 1,400 4,200
    IgM 250 750
    Haemoglobin 17.5 1,000
    Biotin 0.117 0.351
    Acetaminophen (paracetamol) 5.2 15.6
    Acetylsalicylic acid (asprin) 1 3
    Ibuprofen 7.3 22
    Caffeine 3.6 11
  • This SARS-CoV-2 IgG antibody test is CE marked for professional use by healthcare professionals, such as doctors, nurses, pharmacists and healthcare workers, and meets UK and European Union (EU) health and safety requirements.

    Laboratory professionals or trained lay providers may use the test, also. The test cannot be used by anyone else.

    To request a quote for our rapid antibody test, please visit this page.

    For more information view our AbC-19™ Fact Sheet

  • The following can order AbC-19™:

    • Any organisation who intends to roll out testing conducted by employees or suppliers who meet one of the criteria for ‘Who can use AbC-19™’.
    • Medical device distributors
    • Healthcare organisations such as hospitals, health clinics, testing centres, pharmacists etc
    • Laboratories

    Click here to request a quote for the AbC-19™ rapid neutralising antibody test.

  • From a finger-prick sample of blood, AbC-19™ antibody rapid test detects the SARS-CoV-2 IgG neutralising antibodies to the full spike protein produced in response to the virus or following vaccination. The rapid antibody test will determine if the body has produced a measurable immune response indicating a previous infection with COVID-19 virus or vaccination. It will not confirm if you are currently infected by the virus.

    For more information view our AbC-19™ Fact Sheet

     

  • AbC-19™ was developed by UK lateral flow manufacturer Abingdon Health on behalf of the UK Rapid Test Consortium (UK-RTC). Led by Abingdon Health, AbC-19™ is manufactured across several UK sites.

    About Abingdon Health

    Abingdon Health plc is a world leading developer and manufacturer of high-quality lateral flow rapid tests across all industry sectors, including healthcare and COVID-19. Abingdon Health is the partner of choice for a growing global customer base and takes projects from initial concept through to routine and large-scale manufacturing and has also developed and marketed its own lateral flow products.

    • Lateral flow experts with a combined 150+ years of development and manufacturing experience
    • Multiple state-of-the-art manufacturing facilities
    • Capacity to manufacture millions of test each month
    • Certified to ISO 9001 and ISO 13485. See our quality standards page.
    • International logistics partners
    • Established network of approved material suppliers
  • The line closest to the sample hole is the test line (T-line). The presence of a T-line alongside a C-line is a POSITIVE result, the absence of a T-Line alongside a C-line is a NEGATIVE result.

  • 25 x AbC-19™ Rapid Tests
    30 x Lancets
    30 x Test Solution Vials (containing 30 units)
    30 x Blood Collectors
    25 x Waste Bags
    1 x IFU (Instructions for Use)

  • For additional assistance when performing and interpreting the AbC-19™ Rapid Test please contact our helpline:
    Tel: +44 (0) 2890 394 258
    Email: abc19support@mplcontact.com

    Support lines are open 24 hours, seven days a week

    Note: questions about ordering or quotations must be directed to customerservices@abingdonhealth.com.

  • Abingdon Health accepts payment in GBP, USD and EUR via BACS, Credit Card or Debit Card. Phone orders can be made at +44 (0) 1904 406082.

    The timeline for shipping orders depends on the size of the order and the shipping locations. All shipments are tracked and charged depending on the size and weight. Shipping costs are in addition to the cost of the tests.

    Our team will confirm shipping costs and details prior to payment.

    If you have any questions or urgent shipping needs, please call +44 (0) 1904 406082 or email customerservices@abingdonhealth.com.